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SECIS elements in the coding regions of selenoprotein transcripts are functional in higher eukaryotes

Expression of selenocysteine (Sec)-containing proteins requires the presence of a cis-acting mRNA structure, called selenocysteine insertion sequence (SECIS) element. In bacteria, this structure is located in the coding region immediately downstream of the Sec-encoding UGA codon, whereas in eukaryot...

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Detalles Bibliográficos
Autores principales: Mix, Heiko, Lobanov, Alexey V., Gladyshev, Vadim N.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802603/
https://www.ncbi.nlm.nih.gov/pubmed/17169995
http://dx.doi.org/10.1093/nar/gkl1060