Analysis of the DNA-binding sequence specificity of the archaeal transcriptional regulator Ss-LrpB from Sulfolobus solfataricus by systematic mutagenesis and high resolution contact probing

To determine the sequence specificity of dimeric Ss-LrpB, a high resolution contact map was constructed and a saturation mutagenesis conducted on one half of the palindromic consensus box. Premodification binding interference indicates that Ss-LrpB establishes most of its tightest contacts with a si...

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Detalles Bibliográficos
Autores principales: Peeters, Eveline, Wartel, Carine, Maes, Dominique, Charlier, Daniel
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802622/
https://www.ncbi.nlm.nih.gov/pubmed/17178749
http://dx.doi.org/10.1093/nar/gkl1095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802622/
https://www.ncbi.nlm.nih.gov/pubmed/17178749
http://dx.doi.org/10.1093/nar/gkl1095

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