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Human RAD18 is involved in S phase-specific single-strand break repair without PCNA monoubiquitination

Switching from a replicative to a translesion polymerase is an important step to further continue on replication at the site of DNA lesion. Recently, RAD18 (a ubiquitin ligase) was shown to monoubiquitinate proliferating cell nuclear antigen (PCNA) in cooperation with RAD6 (a ubiquitin-conjugating e...

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Detalles Bibliográficos
Autores principales: Shiomi, Naoko, Mori, Masahiko, Tsuji, Hideo, Imai, Takashi, Inoue, Hirokazu, Tateishi, Satoshi, Yamaizumi, Masaru, Shiomi, Tadahiro
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802632/
https://www.ncbi.nlm.nih.gov/pubmed/17158148
http://dx.doi.org/10.1093/nar/gkl979