Iloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungs

BACKGROUND: The rapid desensitization of the human prostacyclin (IP) in response to agonist binding has been shown in cell culture. Phosphorylation of the IP receptor by protein kinase C (PKC) has been suggested to be involved in this process. METHODS AND RESULTS: In this study we investigated the v...

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Detalles Bibliográficos
Autores principales: Schermuly, Ralph T, Pullamsetti, Soni S, Breitenbach, Susanne C, Weissmann, Norbert, Ghofrani, Hossein A, Grimminger, Friedrich, Nilius, Sigrid M, Schrör, Karsten, Meger-Kirchrath, Jutta, Seeger, Werner, Rose, Frank
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802745/
https://www.ncbi.nlm.nih.gov/pubmed/17257398
http://dx.doi.org/10.1186/1465-9921-8-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802745/
https://www.ncbi.nlm.nih.gov/pubmed/17257398
http://dx.doi.org/10.1186/1465-9921-8-4

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