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A New Inhibitor of Apoptosis from Vaccinia Virus and Eukaryotes

A new apoptosis inhibitor is described from vaccinia virus, camelpox virus, and eukaryotic cells. The inhibitor is a hydrophobic, multiple transmembrane protein that is resident in the Golgi and is named GAAP (Golgi anti-apoptotic protein). Stable expression of both viral GAAP (v-GAAP) and human GAA...

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Detalles Bibliográficos
Autores principales: Gubser, Caroline, Bergamaschi, Daniele, Hollinshead, Michael, Lu, Xin, van Kuppeveld, Frank J. M, Smith, Geoffrey L
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1803007/
https://www.ncbi.nlm.nih.gov/pubmed/17319741
http://dx.doi.org/10.1371/journal.ppat.0030017