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Mechanism of Ad5 Vaccine Immunity and Toxicity: Fiber Shaft Targeting of Dendritic Cells

Recombinant adenoviral (rAd) vectors elicit potent cellular and humoral immune responses and show promise as vaccines for HIV-1, Ebola virus, tuberculosis, malaria, and other infections. These vectors are now widely used and have been generally well tolerated in vaccine and gene therapy clinical tri...

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Detalles Bibliográficos
Autores principales: Cheng, Cheng, Gall, Jason G. D, Kong, Wing-pui, Sheets, Rebecca L, Gomez, Phillip L, King, C. Richter, Nabel, Gary J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1803013/
https://www.ncbi.nlm.nih.gov/pubmed/17319743
http://dx.doi.org/10.1371/journal.ppat.0030025