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Gene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis

BACKGROUND: Osteoporosis, a disease of decreased bone mineral density represents a significant and growing burden in the western world. Aging population structure and therapeutic use of glucocorticoids have contributed in no small way to the increase in the incidence of this disease. Despite substan...

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Detalles Bibliográficos
Autores principales: Hurson, Conor J, Butler, Joseph S, Keating, Dominic T, Murray, David W, Sadlier, Denise M, O'Byrne, John M, Doran, Peter P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1803771/
https://www.ncbi.nlm.nih.gov/pubmed/17295923
http://dx.doi.org/10.1186/1471-2474-8-12