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Considerations in the identification of functional RNA structural elements in genomic alignments
BACKGROUND: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and score potential RNA secondary structures on the basis of thermodynamic stability, conservation, and/or covariance in seque...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1803800/ https://www.ncbi.nlm.nih.gov/pubmed/17263882 http://dx.doi.org/10.1186/1471-2105-8-33 |