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Upregulation of pirin expression by chronic cigarette smoking is associated with bronchial epithelial cell apoptosis

BACKGROUND: Cigarette smoke disrupts the protective barrier established by the airway epithelium through direct damage to the epithelial cells, leading to cell death. Since the morphology of the airway epithelium of smokers does not typically demonstrate necrosis, the most likely mechanism for epith...

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Detalles Bibliográficos
Autores principales: Gelbman, Brian D, Heguy, Adriana, O'Connor, Timothy P, Zabner, Joseph, Crystal, Ronald G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805431/
https://www.ncbi.nlm.nih.gov/pubmed/17288615
http://dx.doi.org/10.1186/1465-9921-8-10