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Respiratory syncytial virus infection in Fischer 344 rats is attenuated by short interfering RNA against the RSV-NS1 gene

BACKGROUND: Respiratory syncytial virus (RSV) causes severe bronchiolitis and is a risk factor for asthma. Since there is no commercially available vaccine against RSV, a short interfering RNA against the RSV-NS1gene (siNS1) was developed and its potential for decreasing RSV infection and infection-...

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Detalles Bibliográficos
Autores principales: Kong, Xiaoyuan, Zhang, Weidong, Lockey, Richard F, Auais, Alexander, Piedimonte, Giovanni, Mohapatra, Shyam S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805440/
https://www.ncbi.nlm.nih.gov/pubmed/17270047
http://dx.doi.org/10.1186/1479-0556-5-4