Structural analysis of the evolution of steroid specificity in the mineralocorticoid and glucocorticoid receptors

BACKGROUND: The glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) evolved from a common ancestor. Still not completely understood is how specificity for glucocorticoids (e.g. cortisol) and mineralocorticoids (e.g. aldosterone) evolved in these receptors. RESULTS: Our analysis of sever...

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Detalles Bibliográficos
Autores principales: Baker, Michael E, Chandsawangbhuwana, Charlie, Ollikainen, Noah
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805736/
https://www.ncbi.nlm.nih.gov/pubmed/17306029
http://dx.doi.org/10.1186/1471-2148-7-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805736/
https://www.ncbi.nlm.nih.gov/pubmed/17306029
http://dx.doi.org/10.1186/1471-2148-7-24

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