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Structural analysis of the evolution of steroid specificity in the mineralocorticoid and glucocorticoid receptors

BACKGROUND: The glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) evolved from a common ancestor. Still not completely understood is how specificity for glucocorticoids (e.g. cortisol) and mineralocorticoids (e.g. aldosterone) evolved in these receptors. RESULTS: Our analysis of sever...

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Detalles Bibliográficos
Autores principales:	Baker, Michael E, Chandsawangbhuwana, Charlie, Ollikainen, Noah
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805736/ https://www.ncbi.nlm.nih.gov/pubmed/17306029 http://dx.doi.org/10.1186/1471-2148-7-24

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