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Meta-Analysis in Genome-Wide Association Datasets: Strategies and Application in Parkinson Disease

BACKGROUND: Genome-wide association studies hold substantial promise for identifying common genetic variants that regulate susceptibility to complex diseases. However, for the detection of small genetic effects, single studies may be underpowered. Power may be improved by combining genome-wide datas...

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Detalles Bibliográficos
Autores principales: Evangelou, Evangelos, Maraganore, Demetrius M., Ioannidis, John P.A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805816/
https://www.ncbi.nlm.nih.gov/pubmed/17332845
http://dx.doi.org/10.1371/journal.pone.0000196