Deinococcus radiodurans RNA ligase exemplifies a novel ligase clade with a distinctive N-terminal module that is important for 5′-PO(4) nick sealing and ligase adenylylation but dispensable for phosphodiester formation at an adenylylated nick

Deinococcus radiodurans RNA ligase (DraRnl) is a template-directed ligase that seals nicked duplexes in which the 3′-OH strand is RNA. DraRnl is a 342 amino acid polypeptide composed of a C-terminal adenylyltransferase domain fused to a distinctive 126 amino acid N-terminal module (a putative OB-fol...

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Detalles Bibliográficos
Autores principales: Raymond, Amy, Shuman, Stewart
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807946/
https://www.ncbi.nlm.nih.gov/pubmed/17204483
http://dx.doi.org/10.1093/nar/gkl1090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807946/
https://www.ncbi.nlm.nih.gov/pubmed/17204483
http://dx.doi.org/10.1093/nar/gkl1090

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