The accessory subunit B of DNA polymerase γ is required for mitochondrial replisome function

The mitochondrial replication machinery in human cells includes the DNA polymerase γ holoenzyme and the TWINKLE helicase. Together, these two factors form a processive replication machinery, a replisome, which can use duplex DNA as template to synthesize long stretches of single-stranded DNA. We her...

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Detalles Bibliográficos
Autores principales: Farge, Géraldine, Pham, Xuan Hoi, Holmlund, Teresa, Khorostov, Ivan, Falkenberg, Maria
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807957/
https://www.ncbi.nlm.nih.gov/pubmed/17251196
http://dx.doi.org/10.1093/nar/gkl1116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807957/
https://www.ncbi.nlm.nih.gov/pubmed/17251196
http://dx.doi.org/10.1093/nar/gkl1116

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