Positional clustering improves computational binding site detection and identifies novel cis-regulatory sites in mammalian GABA(A) receptor subunit genes

Understanding transcription factor (TF) mediated control of gene expression remains a major challenge at the interface of computational and experimental biology. Computational techniques predicting TF-binding site specificity are frequently unreliable. On the other hand, comprehensive experimental v...

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Detalles Bibliográficos
Autores principales: Reddy, Timothy E., Shakhnovich, Boris E., Roberts, Daniel S., Russek, Shelley J., DeLisi, Charles
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807961/
https://www.ncbi.nlm.nih.gov/pubmed/17204484
http://dx.doi.org/10.1093/nar/gkl1062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807961/
https://www.ncbi.nlm.nih.gov/pubmed/17204484
http://dx.doi.org/10.1093/nar/gkl1062

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