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Contributions of ubiquitin- and PCNA-binding domains to the activity of Polymerase η in Saccharomyces cerevisiae

Bypassing of DNA lesions by damage-tolerant DNA polymerases depends on the interaction of these enzymes with the monoubiquitylated form of the replicative clamp protein, PCNA. We have analyzed the contributions of ubiquitin and PCNA binding to damage bypass and damage-induced mutagenesis in Polymera...

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Detalles Bibliográficos
Autores principales: Parker, Joanne L., Bielen, Aleksandra B., Dikic, Ivan, Ulrich, Helle D.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807963/
https://www.ncbi.nlm.nih.gov/pubmed/17251197
http://dx.doi.org/10.1093/nar/gkl1102