Gene-specific recruitment of positive and negative elongation factors during stimulated transcription of the MKP-1 gene in neuroendocrine cells

MAP kinase phosphatase-1 (MKP-1) controls nuclear MAP kinase activity with important consequences on cell growth or apoptosis. MKP-1 transcription is initiated constitutively but elongation is blocked within exon 1. It is unclear how induction of MKP-1 is controlled. Here, we report that the transcr...

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Detalles Bibliográficos
Autores principales: Fujita, Toshitsugu, Ryser, Stephan, Tortola, Silvia, Piuz, Isabelle, Schlegel, Werner
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807974/
https://www.ncbi.nlm.nih.gov/pubmed/17259211
http://dx.doi.org/10.1093/nar/gkl1138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807974/
https://www.ncbi.nlm.nih.gov/pubmed/17259211
http://dx.doi.org/10.1093/nar/gkl1138

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