Pharmacokinetic investigation of dose proportionality with a 24-hour controlled-release formulation of hydromorphone

BACKGROUND: The purpose of this study was investigate the dose proportionality of a novel, once-daily, controlled-release formulation of hydromorphone that utilizes the OROS(® )Push-Pull™ osmotic pump technology. METHODS: In an open-label, four-way, crossover study, 32 healthy volunteers were random...

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Detalles Bibliográficos
Autores principales: Sathyan, Gayatri, Xu, Emily, Thipphawong, John, Gupta, Suneel K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808051/
https://www.ncbi.nlm.nih.gov/pubmed/17270058
http://dx.doi.org/10.1186/1472-6904-7-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808051/
https://www.ncbi.nlm.nih.gov/pubmed/17270058
http://dx.doi.org/10.1186/1472-6904-7-3

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