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TBK1 Protects Vacuolar Integrity during Intracellular Bacterial Infection

TANK-binding kinase-1 (TBK1) is an integral component of Type I interferon induction by microbial infection. The importance of TBK1 and Type I interferon in antiviral immunity is well established, but the function of TBK1 in bacterial infection is unclear. Upon infection of murine embryonic fibrobla...

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Detalles Bibliográficos
Autores principales: Radtke, Andrea L, Delbridge, Laura M, Balachandran, Siddharth, Barber, Glen N, O'Riordan, Mary X. D
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808071/
https://www.ncbi.nlm.nih.gov/pubmed/17335348
http://dx.doi.org/10.1371/journal.ppat.0030029