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NSAIDs Modulate CDKN2A, TP53, and DNA Content Risk for Progression to Esophageal Adenocarcinoma
BACKGROUND: Somatic genetic CDKN2A, TP53, and DNA content abnormalities are common in many human cancers and their precursors, including esophageal adenocarcinoma (EA) and Barrett's esophagus (BE), conditions for which aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) have been pr...
Autores principales: | Galipeau, Patricia C, Li, Xiaohong, Blount, Patricia L, Maley, Carlo C, Sanchez, Carissa A, Odze, Robert D, Ayub, Kamran, Rabinovitch, Peter S, Vaughan, Thomas L, Reid, Brian J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808095/ https://www.ncbi.nlm.nih.gov/pubmed/17326708 http://dx.doi.org/10.1371/journal.pmed.0040067 |
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