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Distinct mechanisms of loss of IFN-gamma mediated HLA class I inducibility in two melanoma cell lines
BACKGROUND: The inability of cancer cells to present antigen on the cell surface via MHC class I molecules is one of the mechanisms by which tumor cells evade anti-tumor immunity. Alterations of Jak-STAT components of interferon (IFN)-mediated signaling can contribute to the mechanism of cell resist...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808467/ https://www.ncbi.nlm.nih.gov/pubmed/17319941 http://dx.doi.org/10.1186/1471-2407-7-34 |