Absence of Ret Signaling in Mice Causes Progressive and Late Degeneration of the Nigrostriatal System

Support of ageing neurons by endogenous neurotrophic factors such as glial cell line–derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor (BDNF) may determine whether the neurons resist or succumb to neurodegeneration. GDNF has been tested in clinical trials for the treatment of...

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Detalles Bibliográficos
Autores principales: Kramer, Edgar R, Aron, Liviu, Ramakers, Geert M. J, Seitz, Sabine, Zhuang, Xiaoxi, Beyer, Klaus, Smidt, Marten P, Klein, Rüdiger
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808500/
https://www.ncbi.nlm.nih.gov/pubmed/17298183
http://dx.doi.org/10.1371/journal.pbio.0050039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808500/
https://www.ncbi.nlm.nih.gov/pubmed/17298183
http://dx.doi.org/10.1371/journal.pbio.0050039

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