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Absence of Ret Signaling in Mice Causes Progressive and Late Degeneration of the Nigrostriatal System
Support of ageing neurons by endogenous neurotrophic factors such as glial cell line–derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor (BDNF) may determine whether the neurons resist or succumb to neurodegeneration. GDNF has been tested in clinical trials for the treatment of...
Autores principales: | Kramer, Edgar R, Aron, Liviu, Ramakers, Geert M. J, Seitz, Sabine, Zhuang, Xiaoxi, Beyer, Klaus, Smidt, Marten P, Klein, Rüdiger |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808500/ https://www.ncbi.nlm.nih.gov/pubmed/17298183 http://dx.doi.org/10.1371/journal.pbio.0050039 |
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