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Antibody to severe acute respiratory syndrome (SARS)-associated coronavirus spike protein domain 2 cross-reacts with lung epithelial cells and causes cytotoxicity

Both viral effect and immune-mediated mechanism are involved in the pathogenesis of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infection. In this study, we showed that in SARS patient sera there were autoantibodies (autoAbs) that reacted with A549 cells, the type-2 pneumocyt...

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Detalles Bibliográficos
Autores principales: Lin, Y S, Lin, C F, Fang, Y T, Kuo, Y M, Liao, P C, Yeh, T M, Hwa, K Y, Shieh, C C K, Yen, J H, Wang, H J, Su, I J, Lei, H Y
Formato: Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1809466/
https://www.ncbi.nlm.nih.gov/pubmed/16045740
http://dx.doi.org/10.1111/j.1365-2249.2005.02864.x