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APC/C – the master controller of origin licensing?

DNA replication must be tightly controlled to prevent initiation of a second round of replication until mitosis is complete. So far, components of the pre-replicative complex (Cdt1, Cdc6 and geminin) were considered key players in this regulation. In a new study, Machida and Dutta have shown that de...

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Detalles Bibliográficos
Autores principales: Sivaprasad, Umasundari, Machida, Yuichi J, Dutta, Anindya
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810247/
https://www.ncbi.nlm.nih.gov/pubmed/17319958
http://dx.doi.org/10.1186/1747-1028-2-8