Cargando…

The Cluster Variation Method for Efficient Linkage Analysis on Extended Pedigrees

BACKGROUND: Computing exact multipoint LOD scores for extended pedigrees rapidly becomes infeasible as the number of markers and untyped individuals increase. When markers are excluded from the computation, significant power may be lost. Therefore accurate approximate methods which take into account...

Descripción completa

Detalles Bibliográficos
Autores principales: Albers, Cornelis A, Leisink, Martijn AR, Kappen, Hilbert J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810310/
https://www.ncbi.nlm.nih.gov/pubmed/16723002
http://dx.doi.org/10.1186/1471-2105-7-S1-S1