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The Cluster Variation Method for Efficient Linkage Analysis on Extended Pedigrees
BACKGROUND: Computing exact multipoint LOD scores for extended pedigrees rapidly becomes infeasible as the number of markers and untyped individuals increase. When markers are excluded from the computation, significant power may be lost. Therefore accurate approximate methods which take into account...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810310/ https://www.ncbi.nlm.nih.gov/pubmed/16723002 http://dx.doi.org/10.1186/1471-2105-7-S1-S1 |