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The Role of Cytokines which Signal through the Common γ Chain Cytokine Receptor in the Reversal of HIV Specific CD4(+) and CD8(+) T Cell Anergy

BACKGROUND: HIV specific T cells are putatively anergic in vivo. IL-2, a member of a class of cytokines that binds to receptors containing the common gamma chain (γc) has been shown to reverse anergy. We examined the role of γc cytokines in reversing HIV specific T cell anergy. METHODS: PBMC from un...

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Detalles Bibliográficos
Autores principales: Gu, Xiao Xiao Jenny, Yue, Feng Yun, Kovacs, Colin M., Ostrowski, Mario A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810433/
https://www.ncbi.nlm.nih.gov/pubmed/17375186
http://dx.doi.org/10.1371/journal.pone.0000300