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Pharmacokinetic profile of a 24-hour controlled-release OROS(® )formulation of hydromorphone in the presence and absence of food

BACKGROUND: The objective of this study was to compare the pharmacokinetic profile of a novel, once-daily, controlled-release formulation of hydromorphone (OROS(® )hydromorphone) under fasting conditions with that immediately after a high-fat breakfast in healthy volunteers. The effect of the opioid...

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Detalles Bibliográficos
Autores principales: Sathyan, Gayatri, Xu, Emily, Thipphawong, John, Gupta, Suneel K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810515/
https://www.ncbi.nlm.nih.gov/pubmed/17270055
http://dx.doi.org/10.1186/1472-6904-7-2