Alterations in lipid metabolism gene expression and abnormal lipid accumulation in fibroblast explants from giant axonal neuropathy patients

BACKGROUND: Giant axonal neuropathy (GAN) is a hereditary neurological disorder that affects both central and peripheral nerves. The main pathological hallmark of the disease is abnormal accumulations of intermediate filaments (IFs) in giant axons and other cell types. Mutations in the GAN gene, enc...

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Detalles Bibliográficos
Autores principales: Leung, Conrad L, Pang, Yinghua, Shu, Chang, Goryunov, Dmitry, Liem, Ronald KH
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810559/
https://www.ncbi.nlm.nih.gov/pubmed/17331252
http://dx.doi.org/10.1186/1471-2156-8-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810559/
https://www.ncbi.nlm.nih.gov/pubmed/17331252
http://dx.doi.org/10.1186/1471-2156-8-6

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