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The effects of DNA methylation and histone deacetylase inhibitors on human papillomavirus early gene expression in cervical cancer, an in vitro and clinical study

BACKGROUND: The methylation status at the human papilloma virus (HPV) genome found in pre-invasive and invasive cervical lesions suggests that neoplastic transformation can be suppressed by gene hypermethylation, whereas hypomethylation accompanies or causes cancer progression; hence, epigenetic the...

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Detalles Bibliográficos
Autores principales: de la Cruz-Hernández, Erick, Pérez-Cárdenas, Enrique, Contreras-Paredes, Adriana, Cantú, David, Mohar, Alejandro, Lizano, Marcela, Dueñas-González, Alfonso
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1819371/
https://www.ncbi.nlm.nih.gov/pubmed/17324262
http://dx.doi.org/10.1186/1743-422X-4-18