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In Vivo Reinsertion of Excised Episomes by the V(D)J Recombinase: A Potential Threat to Genomic Stability

It has long been thought that signal joints, the byproducts of V(D)J recombination, are not involved in the dynamics of the rearrangement process. Evidence has now started to accumulate that this is not the case, and that signal joints play unsuspected roles in events that might compromise genomic i...

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Detalles Bibliográficos
Autores principales: Vanura, Katrina, Montpellier, Bertrand, Le, Trang, Spicuglia, Salvatore, Navarro, Jean-Marc, Cabaud, Olivier, Roulland, Sandrine, Vachez, Elodie, Prinz, Immo, Ferrier, Pierre, Marculescu, Rodrig, Jäger, Ulrich, Nadel, Bertrand
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820826/
https://www.ncbi.nlm.nih.gov/pubmed/17298184
http://dx.doi.org/10.1371/journal.pbio.0050043