Ribonuclease Activity of Dis3 Is Required for Mitotic Progression and Provides a Possible Link between Heterochromatin and Kinetochore Function

BACKGROUND: Cellular RNA metabolism has a broad range of functional aspects in cell growth and division, but its role in chromosome segregation during mitosis is only poorly understood. The Dis3 ribonuclease is a key component of the RNA-processing exosome complex. Previous isolation of the dis3-54...

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Detalles Bibliográficos
Autores principales: Murakami, Hiroaki, Goto, Derek B., Toda, Takashi, Chen, Ee Sin, Grewal, Shiv I., Martienssen, Robert A., Yanagida, Mitsuhiro
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820850/
https://www.ncbi.nlm.nih.gov/pubmed/17380189
http://dx.doi.org/10.1371/journal.pone.0000317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820850/
https://www.ncbi.nlm.nih.gov/pubmed/17380189
http://dx.doi.org/10.1371/journal.pone.0000317

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