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Ribonuclease Activity of Dis3 Is Required for Mitotic Progression and Provides a Possible Link between Heterochromatin and Kinetochore Function
BACKGROUND: Cellular RNA metabolism has a broad range of functional aspects in cell growth and division, but its role in chromosome segregation during mitosis is only poorly understood. The Dis3 ribonuclease is a key component of the RNA-processing exosome complex. Previous isolation of the dis3-54...
Autores principales: | Murakami, Hiroaki, Goto, Derek B., Toda, Takashi, Chen, Ee Sin, Grewal, Shiv I., Martienssen, Robert A., Yanagida, Mitsuhiro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820850/ https://www.ncbi.nlm.nih.gov/pubmed/17380189 http://dx.doi.org/10.1371/journal.pone.0000317 |
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