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Cohesin Is Dispensable for Centromere Cohesion in Human Cells

BACKGROUND: Proper regulation of the cohesion at the centromeres of human chromosomes is essential for accurate genome transmission. Exactly how cohesion is maintained and is then dissolved in anaphase is not understood. PRINCIPAL FINDINGS: We have investigated the role of the cohesin complex at cen...

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Detalles Bibliográficos
Autores principales: Díaz-Martínez, Laura A., Giménez-Abián, Juan F., Clarke, Duncan J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820851/
https://www.ncbi.nlm.nih.gov/pubmed/17389909
http://dx.doi.org/10.1371/journal.pone.0000318