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False occurrences of functional motifs in protein sequences highlight evolutionary constraints

BACKGROUND: False occurrences of functional motifs in protein sequences can be considered as random events due solely to the sequence composition of a proteome. Here we use a numerical approach to investigate the random appearance of functional motifs with the aim of addressing biological questions...

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Detalles Bibliográficos
Autores principales: Via, Allegra, Gherardini, Pier Federico, Ferraro, Enrico, Ausiello, Gabriele, Scalia Tomba, Gianpaolo, Helmer-Citterich, Manuela
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1821045/
https://www.ncbi.nlm.nih.gov/pubmed/17331242
http://dx.doi.org/10.1186/1471-2105-8-68