Fully Differentiated HIV-1 Specific CD8+ T Effector Cells Are More Frequently Detectable in Controlled than in Progressive HIV-1 Infection

BACKGROUND: CD8+ T cells impact control of viral infections by direct elimination of infected cells and secretion of a number of soluble factors. In HIV-1 infection, persistent HIV-1 specific IFN-γ+ CD8+ T cell responses are detected in the setting of disease progression, consistent with functional...

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Detalles Bibliográficos
Autores principales: Addo, Marylyn M., Draenert, Rika, Rathod, Almas, Verrill, Cori L., Davis, Benjamin T., Gandhi, Rajesh T., Robbins, Gregory K., Basgoz, Nesli O., Stone, David R., Cohen, Daniel E., Johnston, Mary N., Flynn, Theresa, Wurcel, Alysse G., Rosenberg, Eric S., Altfeld, Marcus, Walker, Bruce D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1824710/
https://www.ncbi.nlm.nih.gov/pubmed/17389912
http://dx.doi.org/10.1371/journal.pone.0000321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1824710/
https://www.ncbi.nlm.nih.gov/pubmed/17389912
http://dx.doi.org/10.1371/journal.pone.0000321

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