Expression of PPARα modifies fatty acid effects on insulin secretion in uncoupling protein-2 knockout mice

AIMS/HYPOTHESIS: In uncoupling protein-2 (UCP2) knockout (KO) mice, protection of beta cells from fatty acid exposure is dependent upon transcriptional events mediated by peroxisome proliferator-activated receptor-α (PPARα). METHODS: PPARα expression was reduced in isolated islets from UCP2KO and wi...

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Detalles Bibliográficos
Autores principales: Fatehi-Hassanabad, Zahra, Chan, Catherine B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828157/
https://www.ncbi.nlm.nih.gov/pubmed/17341307
http://dx.doi.org/10.1186/1743-7075-4-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828157/
https://www.ncbi.nlm.nih.gov/pubmed/17341307
http://dx.doi.org/10.1186/1743-7075-4-6

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