Sp1/Sp3 and DNA-methylation contribute to basal transcriptional activation of human podoplanin in MG63 versus Saos-2 osteoblastic cells

BACKGROUND: Podoplanin is a membrane mucin that, among a series of tissues, is expressed on late osteoblasts and osteocytes. Since recent findings have focussed on podoplanin's potential role as a tumour progression factor, we aimed at identifying regulatory elements conferring PDPN promoter ac...

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Detalles Bibliográficos
Autores principales: Hantusch, Brigitte, Kalt, Romana, Krieger, Sigurd, Puri, Christina, Kerjaschki, Dontscho
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828165/
https://www.ncbi.nlm.nih.gov/pubmed/17343736
http://dx.doi.org/10.1186/1471-2199-8-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828165/
https://www.ncbi.nlm.nih.gov/pubmed/17343736
http://dx.doi.org/10.1186/1471-2199-8-20

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