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The Drosophila RASSF Homolog Antagonizes the Hippo Pathway

Correct organ size is determined by the balance between cell death and proliferation. Perturbation of this delicate balance leads to cancer formation [1]. Hippo (Hpo), the Drosophila ortholog of MST1 and MST2 (Mammalian Sterile 20-like 1 and 2) is a key regulator of a signaling pathway that controls...

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Detalles Bibliográficos
Autores principales: Polesello, Cedric, Huelsmann, Sven, Brown, Nicholas H., Tapon, Nicolas
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828611/
https://www.ncbi.nlm.nih.gov/pubmed/17174922
http://dx.doi.org/10.1016/j.cub.2006.10.060