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(A)Symmetric Stem Cell Replication and Cancer

Most tissues in metazoans undergo continuous turnover due to cell death or epithelial shedding. Since cellular replication is associated with an inherent risk of mutagenesis, tissues are maintained by a small group of stem cells (SCs) that replicate slowly to maintain their own population and that g...

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Detalles Bibliográficos
Autores principales: Dingli, David, Traulsen, Arne, Michor, Franziska
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828703/
https://www.ncbi.nlm.nih.gov/pubmed/17367205
http://dx.doi.org/10.1371/journal.pcbi.0030053