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Modeling Networks of Coupled Enzymatic Reactions Using the Total Quasi-Steady State Approximation

In metabolic networks, metabolites are usually present in great excess over the enzymes that catalyze their interconversion, and describing the rates of these reactions by using the Michaelis–Menten rate law is perfectly valid. This rate law assumes that the concentration of enzyme–substrate complex...

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Detalles Bibliográficos
Autores principales: Ciliberto, Andrea, Capuani, Fabrizio, Tyson, John J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828705/
https://www.ncbi.nlm.nih.gov/pubmed/17367203
http://dx.doi.org/10.1371/journal.pcbi.0030045