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Posttranscriptional Expression Regulation: What Determines Translation Rates?

Recent analyses indicate that differences in protein concentrations are only 20%–40% attributable to variable mRNA levels, underlining the importance of posttranscriptional regulation. Generally, protein concentrations depend on the translation rate (which is proportional to the translational activi...

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Detalles Bibliográficos
Autores principales: Brockmann, Regina, Beyer, Andreas, Heinisch, Jürgen J, Wilhelm, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1829480/
https://www.ncbi.nlm.nih.gov/pubmed/17381238
http://dx.doi.org/10.1371/journal.pcbi.0030057