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Calcium-activated potassium channels mediated blood-brain tumor barrier opening in a rat metastatic brain tumor model

BACKGROUND: The blood-brain tumor barrier (BTB) impedes the delivery of therapeutic agents to brain tumors. While adequate delivery of drugs occurs in systemic tumors, the BTB limits delivery of anti-tumor agents into brain metastases. RESULTS: In this study, we examined the function and regulation...

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Detalles Bibliográficos
Autores principales: Hu, Jinwei, Yuan, Xiangpeng, Ko, MinHee K, Yin, Dali, Sacapano, Manuel R, Wang, Xiao, Konda, Bindu M, Espinoza, Andres, Prosolovich, Ksenia, Ong, John M, Irvin, Dwain, Black, Keith L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1831484/
https://www.ncbi.nlm.nih.gov/pubmed/17359538
http://dx.doi.org/10.1186/1476-4598-6-22