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Target genes of myostatin loss-of-function in muscles of late bovine fetuses

BACKGROUND: Myostatin, a muscle-specific member of the Transforming Growth Factor beta family, negatively regulates muscle development. Double-muscled (DM) cattle have a loss-of-function mutation in their myostatin gene responsible for the hypermuscular phenotype. Thus, these animals are a good mode...

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Detalles Bibliográficos
Autores principales: Cassar-Malek, Isabelle, Passelaigue, Florent, Bernard, Carine, Léger, Jean, Hocquette, Jean-François
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1831773/
https://www.ncbi.nlm.nih.gov/pubmed/17331240
http://dx.doi.org/10.1186/1471-2164-8-63