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THG113.31, a specific PGF2alpha receptor antagonist, induces human myometrial relaxation and BKCa channel activation

BACKGROUND: PGF2alpha exerts a significant contractile effect on myometrium and is central to human labour. THG113.31, a specific non-competitive PGF2alpha receptor (FP) antagonist, exerts an inhibitory effect on myometrial contractility. The BKCa channel is ubiquitously encountered in human uterine...

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Detalles Bibliográficos
Autores principales: Doheny, Helen C, O'Reilly, Michael J, Sexton, Donal J, Morrison, John J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1831777/
https://www.ncbi.nlm.nih.gov/pubmed/17367527
http://dx.doi.org/10.1186/1477-7827-5-10