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THG113.31, a specific PGF2alpha receptor antagonist, induces human myometrial relaxation and BKCa channel activation
BACKGROUND: PGF2alpha exerts a significant contractile effect on myometrium and is central to human labour. THG113.31, a specific non-competitive PGF2alpha receptor (FP) antagonist, exerts an inhibitory effect on myometrial contractility. The BKCa channel is ubiquitously encountered in human uterine...
Autores principales: | Doheny, Helen C, O'Reilly, Michael J, Sexton, Donal J, Morrison, John J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1831777/ https://www.ncbi.nlm.nih.gov/pubmed/17367527 http://dx.doi.org/10.1186/1477-7827-5-10 |
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