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Lack of α-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease
α-synuclein is a small soluble, cytosolic protein which associates with vesicular membranes. It is a component of intracellular Lewy bodies present in Parkinson's disease and a subset of Alzheimer's disease (AD). In addition, early studies identified a fragment of α-synuclein in the amyloi...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1832188/ https://www.ncbi.nlm.nih.gov/pubmed/17367539 http://dx.doi.org/10.1186/1750-1326-2-6 |