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Lack of α-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease

α-synuclein is a small soluble, cytosolic protein which associates with vesicular membranes. It is a component of intracellular Lewy bodies present in Parkinson's disease and a subset of Alzheimer's disease (AD). In addition, early studies identified a fragment of α-synuclein in the amyloi...

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Detalles Bibliográficos
Autores principales: Kallhoff, Verena, Peethumnongsin, Erica, Zheng, Hui
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1832188/
https://www.ncbi.nlm.nih.gov/pubmed/17367539
http://dx.doi.org/10.1186/1750-1326-2-6