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Lack of α-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease

α-synuclein is a small soluble, cytosolic protein which associates with vesicular membranes. It is a component of intracellular Lewy bodies present in Parkinson's disease and a subset of Alzheimer's disease (AD). In addition, early studies identified a fragment of α-synuclein in the amyloi...

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Detalles Bibliográficos
Autores principales:	Kallhoff, Verena, Peethumnongsin, Erica, Zheng, Hui
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1832188/ https://www.ncbi.nlm.nih.gov/pubmed/17367539 http://dx.doi.org/10.1186/1750-1326-2-6

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